Remember when Spiderman wears the symbiote suit and turns into the Black Spiderman. He has a hard time controlling that suit since it has a life of its own. 
Now, in this game, you will surely have a hard time finding all the letters not because of the symbiote suit, but the fact that it is hidden very well. The game will require you to have a 20/20 vision since you need to use your eye in finding all the letters. You need to find all of them before your time expires. The letters that you need to find are listed on the upper portion of the screen.