The story of Diablo is based on the premise of a war between Heaven and Hell. The town of Tristram is under attack by hordes of demons, pouring forth from beneath the ruined Tristram Cathedral, and the player must save the town. As the player delves into the network of Dungeons and the Caves beneath the Catacombs, he discovers more about the Demon Diablo, through large tomes that are found throughout the levels. Eventually, the player reaches the lair of Diablo and must kill him.

Diablo was added in RPG Games.